The Centre for Experimental Medicine at Queen's is focused on conducting high-quality research into the pathogenesis and treatment of major diseases within our strategic research areas. RESEARCH STRENGTHS Research in the Centre falls into four major Research Divisions: Clinical and Experimental Ophthalmology A multidisciplinary team of researchers who translate basic scientific findings into knowledge and therapies with benefit to patients and advances scientific knowledge in ocular cell and molecular biology and normal visual function to understand the mechanisms of ocular disease. Diabetes and Cardiovascular Disease Comprises a group of basic and clinical scientists with overlapping research interests in areas ranging from microvascular biology to tissue remodelling focussed on the molecular pathogenesis of cardiovascular damage driving diabetes-associated complications in the eye, kidney, heart, placenta and other organs. in the context of diabetes. This group employs a wide range of sophisticated techniques from molecular biology and cell culture to in vivo imaging and functional assessment, to investigate the molecular mechanisms of hyperglycaemia-induce loss of both micro- and macrovascular supply to tissues and organs in the diabetic patient. Infection and Immunity This group focuses on delivering high-quality research programmes, spanning state-of-the-art fundamental and discovery research in infection and inflammatory diseases to clinical research. These include internationally competitive programmes investigating the role of innate and adaptive immune responses to infection and tissue injury, the molecular pathogenesis of bacteria and viruses, and how these host- and pathogen-focused programmes might be targeted to develop effective new treatments for major diseases, such as pneumonia, sepsis, cystic fibrosis and multiple sclerosis. Respiratory Disease With a very strong translational research organisation, this group is primarily focused on lung diseases, with major programmes in asthma, cystic fibrosis, lung infection and acute respiratory distress syndrome. This group comprises a highly interactive and collaborative, multidisciplinary research environment between molecular and cellular immunologists, bacteriologists, virologists, and clinical researchers. Underpinned by high quality fundamental research, this group has a strong emphasis on the development of clinical research programmes to explore new therapeutic strategies for inflammatory diseases of the lung.

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